This medication is used with a doctor-approved exercise, behavior change, and reduced-calorie diet program to help you lose weight. It is used by certain overweight people, such as those who are obese or have weight-related medical problems. Losing weight and keeping it off can lessen the many health risks that come with obesity, including heart disease, diabetes, high blood pressure, and a shorter life. Liraglutide is similar to a natural hormone in your body (incretin). It works by controlling your appetite.
It is a glucagon-like peptide-1 receptor agonist and should not be used in combination with any other drug belonging to this class, including Victoza, a treatment for type 2 diabetes; while Saxenda and Victoza contain the same active ingredient (liraglutide) at different doses, Saxenda is not indicated for the treatment of type 2 diabetes, as the safety and efficacy of Saxenda for the treatment of diabetes has not been established. The cardiovascular safety of liraglutide is being investigated in an ongoing cardiovascular outcomes trial.
Chronic diseases like obesity usually require long-term treatment. Your health care provider will create a plan tailored to your weight-management goals. You’ll need to visit your health care provider 4 months after you begin taking Saxenda to review your progress and renew your prescription. You’ll also work with your health care provider to follow a low-calorie meal plan and increase your physical activity while taking Saxenda for weight management.
WHO CAN USE SAXENDA
Saxenda is licensed to treat obesity in people with a body mass index (BMI) of 30kg/m2 or higher, or those with a BMI of 27kg/m2 to 30kg/m2 who have one or more of a number of weight-linked health conditions including Type 2 diabetes mellitus, hyperlipidemia (raised fat or cholesterol levels in the blood), high blood pressure and obstructive sleep apnea. It should be used in combination with a reduced-calorie diet and regular exercise. Children and young people under the age of 18 should not use Saxenda, as it is not yet known how the drug affects this age group. Furthermore, Saxenda should not be used by pregnant or breastfeeding women due to unknown effects on the fetus or baby.
Nausea, vomiting, stomach upset, diarrhea, gas, heartburn, or constipation may occur. Nausea usually lessens as you continue to use liraglutide. If any of these effects persist or worsen, tell your doctor or pharmacist promptly. Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.
Persistent vomiting/diarrhea may result in a serious loss of body water (dehydration). Contact your doctor promptly if you notice any symptoms of dehydration, such as unusual dry mouth/thirst or dizziness/lightheadedness. Tell your doctor right away if you have any serious side effects, including: signs of kidney problems (such as change in the amount of urine), yellowing eyes/skin, fast heartbeat, mental/mood changes (such as depression, thoughts of suicide), signs of low blood sugar (sudden sweating, shaking, fast heartbeat, hunger, blurred vision, dizziness, or tingling hands/feet). Get medical help right away if you have any very serious side effects, including: signs of pancreatitis or gallbladder disease (such as persistent nausea/vomiting, severe stomach/abdominal pain). A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.
You should talk to your doctor to make sure Saxenda is safe for you. Your health care provider will evaluate your health history and your medical conditions to decide if you can use the medication and if it is likely to improve your health. Do not share your Saxenda pen with others even if the needle has been changed. You may give other people a serious infection or get a serious infection from them.
WHO SHOULD NOT USE SAXENDA
Do not use Saxenda if:
- you or any of your family have ever had MTC or if you have MEN 2.
- you are allergic to liraglutide or any of the ingredients in Saxenda.
- you are pregnant or plan to become pregnant. Saxenda may harm your unborn baby.
Before taking Saxenda, tell your healthcare provider about all of your medical conditions, including if you:
- are taking certain medicines called GLP-1 receptor agonists.
- have severe problems with your stomach, such as slowed emptying of your stomach (gastroparesis) or problems with digesting food.
- have or have had problems with your pancreas, kidneys or liver.
- have or have had depression or suicidal thoughts, or mental health issues.
- are breastfeeding or plan to breastfeed. It is not known if Saxenda® passes into your breast milk. You and your health care provider should decide if you will use Saxenda® or breastfeed.
Tell your healthcare provider about all the medicines you take, including prescription, over-the-counter medicines, vitamins, and herbal supplements. Saxenda slows stomach emptying and can affect medicines that need to pass through the stomach quickly. Saxenda may affect the way some medicines work and some other medicines may affect the way Saxenda works. Tell your health care provider if you take diabetes medicines, especially insulin and sulfonylurea medicines.
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