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What is Yentreve?


Yentreve is a medicine containing the active substance duloxetine. It is available as blue (20 mg) and orange (40 mg) capsules.


Yentreve is indicated for women for the treatment of moderate to severe stress urinary incontinence (SUI). SUI is accidental leaks of urine during physical exertion or when coughing, laughing, sneezing, lifting or exercising. The medicine can only be obtained with a prescription.

How is Yentreve used?

The recommended dose of Yentreve is 40 mg twice a day. Some patients may benefit from starting treatment at a dose of 20 mg twice a day for two weeks before increasing to 40 mg twice a day, to reduce nausea (feeling sick) and dizziness. The benefit of treatment should be re-assessed at regular intervals. Combining Yentreve with pelvic-floor-muscle training may provide additional benefit.


How does Yentreve work?


The active substance in Yentreve, duloxetine, is a serotonin-noradrenaline re-uptake inhibitor (SNRI). It works by preventing the neurotransmitters 5-hydroxytryptamine (also called serotonin) and noradrenaline from being taken back up into nerve cells in the brain and spinal cord.

Neurotransmitters are chemicals that allow nerve cells to communicate with one another. By blocking their re-uptake, duloxetine increases the amount of these neurotransmitters in the spaces between these nerve cells, increasing the level of communication between the cells.


HoneyBee Pharmacy offers best priced* guaranteed. Although HoneyBee Pharmacy is not covered by Medicare, HoneyBee Pharmacy offers medical expense reports that you may submit to your local insurance companies. Should you be reimbursed that is separate from us. HoneyBee Pharmacy also offers best priced* guaranteed for all medications for more information simply give us a call at 1-888-557-0340.

ATTENTION REQUIRED: All customer support calls and chats will be with English Reps. Should you require additional assistance in Spanish please send us an email to info@honeybeepharmacy.com a member of our chat team and email support will send you emails in Spanish.

SHIPPING ADVISORY: Please be advised that due to Covid-19, Canada Post and USPS have both removed their shipping guarantee. Therefore, orders may take 7-10 business days to receive. Please be sure to place your order sooner rather than later. Should you not receive your medication within the quoted time please do not hesitate to give us a call at our toll free number 1 (888) 557-0340 to speak to a member of our customer support team. Thank you.

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Due to Covid-19 both USPS AND CANADA POST have removed their shipping guarantees. Therefore, orders may take 7-10 business days to receive from the date shipped. We ask all new and returning customers to place their orders prior to your own personal supplies running low. Please order ahead of time. We thank you for your cooperation


If you have any questions or would like to speak to a Pharmacist from our contracted Pharmacy department, please do not hesitate to give us a call at our toll free number: 1-888-557-0340.