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Mirabegron is a sympathomimetic beta-3 adrenergic receptor agonist used to relax the smooth muscle of the bladder in the treatment of urinary frequency and incontinence. It is unique amongst overactive bladder treatment options in that, unlike other treatments such as solifenacin and darifenacin, it lacks significant antimuscarinic activity,3 which is responsible both for the therapeutic effects of these medications and their broad range of adverse effects. Mirabegron has a comparatively favorable adverse effect profile as compared to other available treatment options, and its complementary mechanism to the antimuscarinics that came before it allows for its use alongside solifenacin in refractory cases.


Mirabegron first received FDA approval in 2012, under the brand name Myrbetriq, for the treatment of adults with overactive bladder.6 An extended-release granule formulation was subsequently granted approval in March 2021 for the treatment of pediatric patients with neurogenic detrusor overactivity.6 Mirabegron is also used in other jurisdictions across the globe, including Canada,7 the EU,8 and Japan.




Mirabegron is indicated for the treatment of overactive bladder (OAB) – with symptoms of urge urinary incontinence, urgency, and urinary frequency – either alone or in combination with solifenacin.6 It is also indicated for the treatment of neurogenic detrusor overactivity (NDO) in pediatric patients 3 years of age and older and weighing 35kg or more.




You should not use mirabegron if you have uncontrolled hypertension (high blood pressure).




You should not use mirabegron if you are allergic to it.

Tell your doctor if you  ever had:

  • high blood pressure;
  • a bladder obstruction;
  • trouble emptying your bladder (very little urine or a weak stream of urine);
  • kidney disease; or
  • liver disease.



If you develop hives, difficulty breathing, or swelling of your face, lips, tongue, or neck, stop using mirabegron and get emergency medical attention.

Contact your doctor  if you experience any of the following symptoms:

  • When you urinate, you may experience pain or a burning sensation; or
  • High blood pressure can cause severe headaches, impaired vision, and pounding in your neck or ears.

The following are examples of common side effects:

  • Urination that is excruciatingly unpleasant;
  • elevated blood pressure;
  • Sore throat, sinus ache
  • constipation;
  • or a headache
  • dry mouth or fast heartbeats (when taken with solifenacin).



If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 911. Otherwise, call a poison control center right away.




Store at room temperature away from light and moisture. Do not store in the bathroom. Keep all medications away from children and pets.

HoneyBee Pharmacy offers best priced* guaranteed. Although HoneyBee Pharmacy is not covered by Medicare, HoneyBee Pharmacy offers medical expense reports that you may submit to your local insurance companies. Should you be reimbursed that is separate from us. HoneyBee Pharmacy also offers best priced* guaranteed for all medications for more information simply give us a call at 1-888-557-0340.

ATTENTION REQUIRED: All customer support calls and chats will be with English Reps. Should you require additional assistance in Spanish please send us an email to a member of our chat team and email support will send you emails in Spanish.

SHIPPING ADVISORY: Please be advised that due to Covid-19, Canada Post and USPS have both removed their shipping guarantee. Therefore, orders may take 7-10 business days to receive. Please be sure to place your order sooner rather than later. Should you not receive your medication within the quoted time please do not hesitate to give us a call at our toll free number 1 (888) 557-0340 to speak to a member of our customer support team. Thank you.

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Due to Covid-19 both USPS AND CANADA POST have removed their shipping guarantees. Therefore, orders may take 7-10 business days to receive from the date shipped. We ask all new and returning customers to place their orders prior to your own personal supplies running low. Please order ahead of time. We thank you for your cooperation


If you have any questions or would like to speak to a Pharmacist from our contracted Pharmacy department, please do not hesitate to give us a call at our toll free number: 1-888-557-0340.